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4C8K

Crystal structure of the large fragment of DNA polymerase I from Thermus Aquaticus in a partially closed complex with the artificial base pair d5SICS-dNaMTP

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
DNA POLYMERASE I, THERMOSTABLEpolymer54060937.01UniProt (P19821)
Pfam (PF09281)
Pfam (PF00476)
THERMUS AQUATICUSTAQ POLYMERASE 1, LARGE FRAGMENT OF TAQ DNA POLYMERASE I
2B
(B)
5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*C*DOC)-3'polymer123617.41SYNTHETIC CONSTRUCT
3C
(C)
5'-D(*AP*AP*C*LHOP*GP*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3'polymer164964.31SYNTHETIC CONSTRUCT
4D, H
(A, C)
GLYCEROLnon-polymer92.12Chemie (GOL)
5E
(A)
((2R,3S,5R)-3-hydroxy-5-(3-methoxynaphthalen-2-yl)methyl-tetrahydrogen-triphosphatenon-polymer514.31Chemie (BMR)
6F, G
(A, B)
MAGNESIUM IONnon-polymer24.32Chemie (MG)
7I
(C)
2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOLnon-polymer122.11Chemie (TRS)
8J, K, L
(A, B, C)
waterwater18.0144Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight69518.7
Non-Polymers*Number of molecules6
Total formula weight869.2
All*Total formula weight70387.8
*Water molecules are not included.

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PDB entries from 2025-07-09

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