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4C8K

Crystal structure of the large fragment of DNA polymerase I from Thermus Aquaticus in a partially closed complex with the artificial base pair d5SICS-dNaMTP

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
DNA POLYMERASE I, THERMOSTABLEpolymer54060937.01UniProt (P19821)THERMUS AQUATICUSTAQ POLYMERASE 1, LARGE FRAGMENT OF TAQ DNA POLYMERASE I
2B
(B)
5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*C*DOC)-3'polymer123617.41SYNTHETIC CONSTRUCT
3C
(C)
5'-D(*AP*AP*C*LHOP*GP*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3'polymer164964.31SYNTHETIC CONSTRUCT
4D, H
(A, C)
GLYCEROLnon-polymer92.12Chemie (GOL)
5E
(A)
((2R,3S,5R)-3-hydroxy-5-(3-methoxynaphthalen-2-yl)methyl-tetrahydrogen-triphosphatenon-polymer514.31Chemie (BMR)
6F, G
(A, B)
MAGNESIUM IONnon-polymer24.32Chemie (MG)
7I
(C)
2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOLnon-polymer122.11Chemie (TRS)
8J, K, L
(A, B, C)
waterwater18.0144Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight69518.7
Non-Polymers*Number of molecules6
Total formula weight869.2
All*Total formula weight70387.8
*Water molecules are not included.

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PDB entries from 2026-02-11

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