4B94

Crystal structure of human Mps1 TPR domain

Summary for 4B94

Entry DOI	10.2210/pdb4b94/pdb
Related	2X9E
Descriptor	DUAL SPECIFICITY PROTEIN KINASE TTK, TETRAETHYLENE GLYCOL, GLYCEROL, ... (7 entities in total)
Functional Keywords	transferase, kinetochore, mitosis
Biological source	HOMO SAPIENS (HUMAN)
Total number of polymer chains	4
Total formula weight	83192.49
Authors	Littler, D.,von Castelmur, E.,De Marco, V.,Perrakis, A. (deposition date: 2012-08-31, release date: 2013-04-24, Last modification date: 2017-12-13)
Primary citation	Nijenhuis, W.,von Castelmur, E.,Littler, D.,De Marco, V.,Tromer, E.,Vleugel, M.,van Osch, M.H.,Snel, B.,Perrakis, A.,Kops, G.J. A Tpr Domain-Containing N-Terminal Module of Mps1 is Required for its Kinetochore Localization by Aurora B. J.Cell Biol., 201:217-, 2013 Cited by PubMed: 23569217 DOI: 10.1083/JCB.201210033 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation