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4B94

Crystal structure of human Mps1 TPR domain

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
DUAL SPECIFICITY PROTEIN KINASE TTKpolymer18120318.14UniProt (P33981)HOMO SAPIENS (HUMAN)MPS1, PHOSPHOTYROSINE PICKED THREONINE-PROTEIN KINASE, PYT
2E, R
(A, D)
TETRAETHYLENE GLYCOLnon-polymer194.22Chemie (PG4)
3F, G, H, J, L...
(A, B, C, D)
GLYCEROLnon-polymer92.110Chemie (GOL)
4I, O
(B, C)
TRIETHYLENE GLYCOLnon-polymer150.22Chemie (PGE)
5K, N
(B)
MALONATE IONnon-polymer102.02Chemie (MLI)
6P
(C)
DI(HYDROXYETHYL)ETHERnon-polymer106.11Chemie (PEG)
7V, W, X, Y
(A, B, C, D)
waterwater18.0232Chemie (HOH)
Sequence modifications
A, B, C, D: 62 - 239 (UniProt: P33981)
PDBExternal DatabaseDetails
Gly -2-expression tag
Pro -1-expression tag
Gly 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight81272.5
Non-Polymers*Number of molecules17
Total formula weight1919.9
All*Total formula weight83192.5
*Water molecules are not included.

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PDB entries from 2024-10-30

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