4B94
Crystal structure of human Mps1 TPR domain
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | DUAL SPECIFICITY PROTEIN KINASE TTK | polymer | 181 | 20318.1 | 4 | UniProt (P33981) | HOMO SAPIENS (HUMAN) | MPS1, PHOSPHOTYROSINE PICKED THREONINE-PROTEIN KINASE, PYT |
| 2 | E, R (A, D) | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 2 | Chemie (PG4) | |||
| 3 | F, G, H, J, L... (A, B, C, D) | GLYCEROL | non-polymer | 92.1 | 10 | Chemie (GOL) | |||
| 4 | I, O (B, C) | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 2 | Chemie (PGE) | |||
| 5 | K, N (B) | MALONATE ION | non-polymer | 102.0 | 2 | Chemie (MLI) | |||
| 6 | P (C) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) | |||
| 7 | V, W, X, Y (A, B, C, D) | water | water | 18.0 | 232 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 62 - 239 (UniProt: P33981)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Pro -1 | - | expression tag |
| Gly 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 81272.5 | |
| Non-Polymers* | Number of molecules | 17 |
| Total formula weight | 1919.9 | |
| All* | Total formula weight | 83192.5 |






