4AZG

Differential inhibition of the tandem GH20 catalytic modules in the pneumococcal exo-beta-D-N-acetylglucosaminidase, StrH

4AZG の概要

• エントリーDOI: 10.2210/pdb4azg/pdb
• 関連するPDBエントリー: 2YL5 2YL6 2YL8 2YL9 2YLA 2YLL 4AZ5 4AZ6 4AZ7 4AZH 4AZI
• 分子名称: BETA-N-ACETYLHEXOSAMINIDASE, O-(2-ACETAMIDO-2-DEOXY D-GLUCOPYRANOSYLIDENE) AMINO-N-PHENYLCARBAMATE, ACETATE ION, ... (5 entities in total)
• 機能のキーワード: hydrolase
• 由来する生物種: STREPTOCOCCUS PNEUMONIAE
• 細胞内の位置: Secreted, cell wall; Peptidoglycan-anchor (Potential): P49610
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 101201.40

構造登録者

Pluvinage, B.,Stubbs, K.A.,Vocadlo, D.J.,Boraston, A.B. (登録日: 2012-06-25, 公開日: 2013-07-10, 最終更新日: 2023-12-20)

• 主引用文献: Pluvinage, B.,Stubbs, K.A.,Vocadlo, D.J.,Boraston, A.B.; Inhibition of the Family 20 Glycoside Hydrolase Catalytic Modules in the Streptococcus Pneumoniae Exo-Beta-D-N-Acetylglucosaminidase, Strh.; Org.Biomol.Chem., 11:7907-, 2013; PubMed: 24132305; DOI: 10.1039/C3OB41579A

実験手法

X-RAY DIFFRACTION (2.4 Å)