4AZG
Differential inhibition of the tandem GH20 catalytic modules in the pneumococcal exo-beta-D-N-acetylglucosaminidase, StrH
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | BETA-N-ACETYLHEXOSAMINIDASE | polymer | 443 | 49790.9 | 2 | UniProt (P49610) Pfam (PF00728) | STREPTOCOCCUS PNEUMONIAE | GLYCOSIDE HYDROLASE 20 |
| 2 | C, L (A, B) | O-(2-ACETAMIDO-2-DEOXY D-GLUCOPYRANOSYLIDENE) AMINO-N-PHENYLCARBAMATE | non-polymer | 353.3 | 2 | Chemie (OAN) | |||
| 3 | D, E, F, M, N... (A, B) | ACETATE ION | non-polymer | 59.0 | 6 | Chemie (ACT) | |||
| 4 | G, H, I, J, K... (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 9 | Chemie (EDO) | |||
| 5 | T, U (A, B) | water | water | 18.0 | 546 | Chemie (HOH) |
Sequence modifications
A, B: 627 - 1064 (UniProt: P49610)
| PDB | External Database | Details |
|---|---|---|
| Arg 622 | - | expression tag |
| Gly 623 | - | expression tag |
| Ser 624 | - | expression tag |
| His 625 | - | expression tag |
| Met 626 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 99581.9 | |
| Non-Polymers* | Number of molecules | 17 |
| Total formula weight | 1619.5 | |
| All* | Total formula weight | 101201.4 |
