4AQX
Crystal structure of I-CreI complexed with its target methylated at position plus 2 (in the b strand) in the presence of magnesium
Summary for 4AQX
Entry DOI | 10.2210/pdb4aqx/pdb |
Related | 1AF5 1BP7 1G9Y 1G9Z 1MOW 1N3E 1N3F 1T9I 1T9J 1U0C 1U0D 2VBJ 2VBL 2VBN 2VBO 4AAB 4AAD 4AAE 4AAF 4AAG 4AQU |
Descriptor | DNA ENDONUCLEASE I-CREI, 5'-D(*TP*CP*AP*AP*AP*AP*CP*GP*TP*CP*GP*TP*GP*AP)-3', 5'-D(*GP*AP*CP*AP*GP*TP*TP*TP*GP*GP)-3', ... (8 entities in total) |
Functional Keywords | hydrolase, methylation, gene targeting, genetics, protein-dna interaction, homing endonucleases |
Biological source | CHLAMYDOMONAS REINHARDTII More |
Cellular location | Plastid, chloroplast: P05725 |
Total number of polymer chains | 6 |
Total formula weight | 50228.28 |
Authors | Valton, J.,Daboussi, F.,Leduc, S.,Redondo, P.,Macmaster, R.,Molina, R.,Montoya, G.,Duchateau, P. (deposition date: 2012-04-19, release date: 2012-07-04, Last modification date: 2023-12-20) |
Primary citation | Valton, J.,Daboussi, F.,Leduc, S.,Molina, R.,Redondo, P.,Macmaster, R.,Montoya, G.,Duchateau, P. 5'-Cytosine-Phosphoguanine (Cpg) Methylation Impacts the Activity of Natural and Engineered Meganucleases. J.Biol.Chem., 287:30139-, 2012 Cited by PubMed: 22740697DOI: 10.1074/JBC.M112.379966 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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