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4AQX

Crystal structure of I-CreI complexed with its target methylated at position plus 2 (in the b strand) in the presence of magnesium

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
DNA ENDONUCLEASE I-CREIpolymer15217516.12UniProt (P05725)CHLAMYDOMONAS REINHARDTIII-CREI, 23S RRNA INTRON PROTEIN
2C
(C)
5'-D(*TP*CP*AP*AP*AP*AP*CP*GP*TP*CP*GP*TP*GP*AP)-3'polymer144288.81SYNTHETIC CONSTRUCT
3D
(D)
5'-D(*GP*AP*CP*AP*GP*TP*TP*TP*GP*GP)-3'polymer103100.01SYNTHETIC CONSTRUCT
4E
(E)
5'-D(*CP*CP*AP*AP*AP*CP*TP*GP*TP*CP*TP*CP*AP*5CM)-3'polymer144198.81SYNTHETIC CONSTRUCT
5F
(F)
5'-D(*GP*AP*CP*GP*TP*TP*TP*TP*GP*AP)-3'polymer103075.01SYNTHETIC CONSTRUCT
6G, H, I, J, K
(A, B, C)
GLYCEROLnon-polymer92.15Chemie (GOL)
7L, M, N
(D, F)
MAGNESIUM IONnon-polymer24.33Chemie (MG)
8O, P, Q, R, S...
(A, B, C, D, E...)
waterwater18.0133Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains6
Total formula weight49694.9
Non-Polymers*Number of molecules8
Total formula weight533.4
All*Total formula weight50228.3
*Water molecules are not included.

247947

PDB entries from 2026-01-21

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