4A04

Structure of the DNA-bound T-box domain of human TBX1, a transcription factor associated with the DiGeorge syndrome

Summary for 4A04

Entry DOI	10.2210/pdb4a04/pdb
Descriptor	T-BOX TRANSCRIPTION FACTOR TBX1, DNA (3 entities in total)
Functional Keywords	transcription, t-box proteins, protein-dna interaction
Biological source	HOMO SAPIENS (HUMAN) More
Cellular location	Nucleus (Potential): O43435
Total number of polymer chains	4
Total formula weight	62403.92
Authors	El Omari, K.,De Mesmaeker, J.,Karia, D.,Ginn, H.,Bhattacharya, S.,Mancini, E.J. (deposition date: 2011-09-07, release date: 2011-10-12, Last modification date: 2023-12-20)
Primary citation	El Omari, K.,De Mesmaeker, J.,Karia, D.,Ginn, H.,Bhattacharya, S.,Mancini, E.J. Structure of the DNA-Bound T-Box Domain of Human Tbx1, a Transcription Factor Associated with the Digeorge Syndrome Proteins, 80:655-, 2012 Cited by PubMed: 22095455 DOI: 10.1002/PROT.23208 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.58 Å)

Structure validation