4KFM
Crystal structure of the G protein-gated inward rectifier K+ channel GIRK2 (Kir3.2) in complex with the beta-gamma G protein subunits
Summary for 4KFM
Entry DOI | 10.2210/pdb4kfm/pdb |
Related | 3SYA 3SYC 3SYO 3SYP 3SYQ |
Descriptor | G protein-activated inward rectifier potassium channel 2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (7 entities in total) |
Functional Keywords | metal transport, ion channel, potassium channel, inward rectification, sodium binding, pip2 binding, g protein binding |
Biological source | Mus musculus (mouse) More |
Cellular location | Membrane; Multi-pass membrane protein (By similarity): Q8C4T8 Cell membrane; Lipid-anchor; Cytoplasmic side (Potential): P59768 |
Total number of polymer chains | 3 |
Total formula weight | 85672.47 |
Authors | Whorton, M.R.,MacKinnon, R. (deposition date: 2013-04-27, release date: 2013-06-12, Last modification date: 2013-09-11) |
Primary citation | Whorton, M.R.,MacKinnon, R. X-ray structure of the mammalian GIRK2-beta gamma G-protein complex. Nature, 498:190-197, 2013 Cited by PubMed: 23739333DOI: 10.1038/nature12241 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.45 Å) |
Structure validation
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