4K4G
Ternary crystal structures of human DNA POLYMERASE LAMBDA IN COMPLEX WITH DNA AND L-DCTP.
Summary for 4K4G
Entry DOI | 10.2210/pdb4k4g/pdb |
Related | 4K4H 4K4I |
Descriptor | DNA polymerase lambda, DNA (5'-D(*CP*GP*GP*CP*GP*GP*TP*AP*CP*TP*G)-3'), DNA (5'-D(*CP*AP*GP*TP*AP*C)-3'), ... (9 entities in total) |
Functional Keywords | dna polymerase, dna repair, phosphoryl transfer reaction, transferase-dna complex, transferase/dna |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus: Q9UGP5 |
Total number of polymer chains | 16 |
Total formula weight | 181642.79 |
Authors | |
Primary citation | Vyas, R.,Zahurancik, W.J.,Suo, Z. Structural basis for the binding and incorporation of nucleotide analogs with L-stereochemistry by human DNA polymerase lambda. Proc.Natl.Acad.Sci.USA, 111:E3033-E3042, 2014 Cited by PubMed: 25015085DOI: 10.1073/pnas.1401286111 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.15 Å) |
Structure validation
Download full validation report