4IZ7
Structure of Non-Phosphorylated ERK2 bound to the PEA-15 Death Effector Domain
Summary for 4IZ7
Entry DOI | 10.2210/pdb4iz7/pdb |
Related | 4IZ5 4IZA |
Descriptor | Mitogen-activated protein kinase 1, Astrocytic phosphoprotein PEA-15, SODIUM ION, ... (4 entities in total) |
Functional Keywords | map kinase, death effector domain, transferase |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasm, cytoskeleton, spindle (By similarity): P28482 Cytoplasm: Q9Z297 |
Total number of polymer chains | 3 |
Total formula weight | 93457.90 |
Authors | Mace, P.D.,Robinson, H.,Riedl, S.J. (deposition date: 2013-01-29, release date: 2013-04-10, Last modification date: 2024-02-28) |
Primary citation | Mace, P.D.,Wallez, Y.,Egger, M.F.,Dobaczewska, M.K.,Robinson, H.,Pasquale, E.B.,Riedl, S.J. Structure of ERK2 bound to PEA-15 reveals a mechanism for rapid release of activated MAPK. Nat Commun, 4:1681-1681, 2013 Cited by PubMed: 23575685DOI: 10.1038/ncomms2687 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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