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4IZA

Structure of Dually Phosphorylated ERK2 bound to the PEA-15 Death Effector Domain

Summary for 4IZA
Entry DOI10.2210/pdb4iza/pdb
Related4IZ5 4IZ7
DescriptorMitogen-activated protein kinase 1, Astrocytic phosphoprotein PEA-15 (3 entities in total)
Functional Keywordsmap kinase, death effector domain, transferase
Biological sourceHomo sapiens (human)
More
Cellular locationCytoplasm, cytoskeleton, spindle (By similarity): P28482
Cytoplasm: Q15121
Total number of polymer chains3
Total formula weight93754.82
Authors
Mace, P.D.,Robinson, H.,Riedl, S.J. (deposition date: 2013-01-29, release date: 2013-04-10, Last modification date: 2013-04-24)
Primary citationMace, P.D.,Wallez, Y.,Egger, M.F.,Dobaczewska, M.K.,Robinson, H.,Pasquale, E.B.,Riedl, S.J.
Structure of ERK2 bound to PEA-15 reveals a mechanism for rapid release of activated MAPK.
Nat Commun, 4:1681-1681, 2013
Cited by
PubMed: 23575685
DOI: 10.1038/ncomms2687
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.93 Å)
Structure validation

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