4IZ7
Structure of Non-Phosphorylated ERK2 bound to the PEA-15 Death Effector Domain
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (C, A) | Mitogen-activated protein kinase 1 | polymer | 356 | 41098.2 | 2 | UniProt (P28482) Pfam (PF00069) | Homo sapiens (human) | MAP kinase 1, MAPK 1, ERT1, Extracellular signal-regulated kinase 2, ERK-2, MAP kinase isoform p42, p42-MAPK, Mitogen-activated protein kinase 2, MAP kinase 2, MAPK 2 |
| 2 | C (B) | Astrocytic phosphoprotein PEA-15 | polymer | 97 | 11238.5 | 1 | UniProt (Q9Z297) Pfam (PF01335) | Cricetulus griseus (Chinese hamsters) | 15 kDa phosphoprotein enriched in astrocytes |
| 3 | D (A) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 4 | E, F, G (C, A, B) | water | water | 18.0 | 649 | Chemie (HOH) |
Sequence modifications
C, A: 8 - 360 (UniProt: P28482)
B: 1 - 96 (UniProt: Q9Z297)
| PDB | External Database | Details |
|---|---|---|
| Gly 5 | - | expression tag |
| Pro 6 | - | expression tag |
| Gly 7 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 93434.9 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 23.0 | |
| All* | Total formula weight | 93457.9 |
