4IZ5
Structure of the complex between ERK2 phosphomimetic mutant and PEA-15
Summary for 4IZ5
Entry DOI | 10.2210/pdb4iz5/pdb |
Related | 4IZ7 4IZA |
Descriptor | Mitogen-activated protein kinase 1, Astrocytic phosphoprotein PEA-15, ADENOSINE-5'-DIPHOSPHATE, ... (4 entities in total) |
Functional Keywords | map kinase, death effector domain, transferase |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasm, cytoskeleton, spindle (By similarity): P28482 Cytoplasm: Q15121 |
Total number of polymer chains | 8 |
Total formula weight | 229124.17 |
Authors | Mace, P.D.,Robinson, H.,Riedl, S.J. (deposition date: 2013-01-29, release date: 2013-04-10, Last modification date: 2024-02-28) |
Primary citation | Mace, P.D.,Wallez, Y.,Egger, M.F.,Dobaczewska, M.K.,Robinson, H.,Pasquale, E.B.,Riedl, S.J. Structure of ERK2 bound to PEA-15 reveals a mechanism for rapid release of activated MAPK. Nat Commun, 4:1681-1681, 2013 Cited by PubMed: 23575685DOI: 10.1038/ncomms2687 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.19 Å) |
Structure validation
Download full validation report