4A4V

Ligand binding domain of human PPAR gamma in complex with amorfrutin 2

Summary for 4A4V

Entry DOI	10.2210/pdb4a4v/pdb
Related	1FM6 1FM9 1I7I 1K74 1KNU 1NYX 1PRG 1RDT 1WM0 1ZGY 2F4B 2FVJ 2G0G 2G0H 2PRG 2VSR 2VST 2VV0 2VV1 2VV2 2VV3 2VV4 2XKW 2YFE 3PRG 4A4W 4PRG
Descriptor	PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA, AMORFRUTIN 2 (3 entities in total)
Functional Keywords	receptor, agonist, diabetes, insulin resistance
Biological source	HOMO SAPIENS (HUMAN)
Cellular location	Nucleus: P37231
Total number of polymer chains	2
Total formula weight	66000.44
Authors	de Groot, J.C.,Weidner, C.,Krausze, J.,Kawamoto, K.,Schroeder, F.C.,Sauer, S.,Buessow, K. (deposition date: 2011-10-20, release date: 2012-10-03, Last modification date: 2023-12-20)
Primary citation	De Groot, J.C.,Weidner, C.,Krausze, J.,Kawamoto, K.,Schroeder, F.C.,Sauer, S.,Bussow, K. Structural Characterization of Amorfrutins Bound to the Peroxisome Proliferator-Activated Receptor Gamma. J.Med.Chem., 56:1535-, 2013 Cited by PubMed: 23286787 DOI: 10.1021/JM3013272 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation