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4A4V

Ligand binding domain of human PPAR gamma in complex with amorfrutin 2

Functional Information from GO Data
ChainGOidnamespacecontents
A0003677molecular_functionDNA binding
A0004879molecular_functionnuclear receptor activity
A0005634cellular_componentnucleus
A0006355biological_processregulation of DNA-templated transcription
B0003677molecular_functionDNA binding
B0004879molecular_functionnuclear receptor activity
B0005634cellular_componentnucleus
B0006355biological_processregulation of DNA-templated transcription
Functional Information from PDB Data
site_idAC1
Number of Residues6
DetailsBINDING SITE FOR RESIDUE YFD A 999
ChainResidue
ACYS285
AARG288
AILE341
ASER342
AMET348
AHOH2077

site_idAC2
Number of Residues9
DetailsBINDING SITE FOR RESIDUE YFD B 999
ChainResidue
BILE326
BMET329
BLEU330
BLEU333
BLEU340
BHOH2069
BCYS285
BARG288
BALA292

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues6
DetailsBINDING: BINDING => ECO:0000269|PubMed:9744270, ECO:0007744|PDB:2PRG
ChainResidueDetails
AGLN314
AGLU351
ATYR477
BGLN314
BGLU351
BTYR477

site_idSWS_FT_FI2
Number of Residues4
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:36737649
ChainResidueDetails
AMET252
BMET252

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PDB entries from 2024-11-06

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