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4PRG

0072 PARTIAL AGONIST PPAR GAMMA COCRYSTAL

Summary for 4PRG
Entry DOI10.2210/pdb4prg/pdb
DescriptorPROTEIN (PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA), (+/-)(2S,5S)-3-(4-(4-CARBOXYPHENYL)BUTYL)-2-HEPTYL-4-OXO-5-THIAZOLIDINE (2 entities in total)
Functional Keywordsthiazolidinone, ligand-binding domain, nuclear receptor, orphan receptor, receptor
Biological sourceHomo sapiens (human)
Total number of polymer chains4
Total formula weight125794.75
Authors
Milburn, M.V. (deposition date: 1999-05-07, release date: 1999-05-27, Last modification date: 2023-12-27)
Primary citationOberfield, J.L.,Collins, J.L.,Holmes, C.P.,Goreham, D.M.,Cooper, J.P.,Cobb, J.E.,Lenhard, J.M.,Hull-Ryde, E.A.,Mohr, C.P.,Blanchard, S.G.,Parks, D.J.,Moore, L.B.,Lehmann, J.M.,Plunket, K.,Miller, A.B.,Milburn, M.V.,Kliewer, S.A.,Willson, T.M.
A peroxisome proliferator-activated receptor gamma ligand inhibits adipocyte differentiation.
Proc.Natl.Acad.Sci.USA, 96:6102-6106, 1999
Cited by
PubMed: 10339548
DOI: 10.1073/pnas.96.11.6102
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.9 Å)
Structure validation

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