1WM0
PPARgamma in complex with a 2-BABA compound
Summary for 1WM0
Entry DOI | 10.2210/pdb1wm0/pdb |
Descriptor | Peroxisome proliferator activated receptor gamma, 14-mer from Nuclear receptor coactivator 2, 2-[(2,4-DICHLOROBENZOYL)AMINO]-5-(PYRIMIDIN-2-YLOXY)BENZOIC ACID (3 entities in total) |
Functional Keywords | three-layer helical domain, transcription-signaling protein complex, transcription/signaling protein |
Biological source | Homo sapiens (human) More |
Cellular location | Membrane; Single-pass type I membrane protein (Potential): Q96J12 Nucleus: Q61026 |
Total number of polymer chains | 2 |
Total formula weight | 35382.64 |
Authors | Ostberg, T.,Svensson, S.,Selen, G.,Uppenberg, J.,Thor, M.,Sundbom, M.,Sydow-Backman, M.,Gustavsson, A.L.,Jendeberg, L. (deposition date: 2004-07-01, release date: 2004-09-07, Last modification date: 2024-03-13) |
Primary citation | Ostberg, T.,Svensson, S.,Selen, G.,Uppenberg, J.,Thor, M.,Sundbom, M.,Sydow-Backman, M.,Gustavsson, A.L.,Jendeberg, L. A new class of peroxisome proliferator-activated receptor agonists with a novel binding epitope shows antidiabetic effects J.Biol.Chem., 279:41124-41130, 2004 Cited by PubMed: 15258145DOI: 10.1074/jbc.M401552200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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