1WM0

PPARgamma in complex with a 2-BABA compound

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (X)	Peroxisome proliferator activated receptor gamma	polymer	292	33227.4	1	UniProt (Q96J12) Pfam (PF00104) UniProt (by SIFTS) (P37231)	Homo sapiens (human)	PPAR-gamma
2	B (Y)	14-mer from Nuclear receptor coactivator 2	polymer	14	1751.1	1	UniProt (Q61026)		NCoA-2, Transcriptional intermediary factor 2, Glucocorticoid receptor-interacting protein 1, GRIP-1
3	C (X)	2-[(2,4-DICHLOROBENZOYL)AMINO]-5-(PYRIMIDIN-2-YLOXY)BENZOIC ACID	non-polymer		404.2	1	Chemie (PLB)

Sequence modifications

X: 204 - 477 (UniProt: Q96J12)

PDB	External Database	Details
Gly 186	-	expression tag
Ser 187	-	expression tag
Ser 188	-	expression tag
His 189	-	expression tag
His 190	-	expression tag
His 191	-	expression tag
His 192	-	expression tag
His 193	-	expression tag
His 194	-	expression tag
Ser 195	-	expression tag
Gly 196	-	expression tag
Ser 197	-	expression tag
Gly 198	-	expression tag
Thr 199	-	expression tag
Ile 200	-	expression tag
Glu 201	-	expression tag
Gly 202	-	expression tag
Arg 203	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	34978.4
Non-Polymers*	Number of molecules	1
	Total formula weight	404.2
All*	Total formula weight	35382.6

*Water molecules are not included.