3ZU7
Crystal structure of a designed selected Ankyrin Repeat protein in complex with the MAP kinase ERK2
Summary for 3ZU7
Entry DOI | 10.2210/pdb3zu7/pdb |
Related | 1ERK 1GOL 2ERK 2GPH 3ERK 3ZUV 4ERK |
Descriptor | MITOGEN-ACTIVATED PROTEIN KINASE 1, DESIGNED ANKYRIN REPEAT PROTEIN (3 entities in total) |
Functional Keywords | transferase-de novo protein complex, transferase, selected binder, protein design, transferase/de novo protein |
Biological source | RATTUS NORVEGICUS (NORWAY RAT) More |
Cellular location | Cytoplasm, cytoskeleton, spindle : P63086 |
Total number of polymer chains | 2 |
Total formula weight | 60558.86 |
Authors | Kummer, L.,Mittl, P.R.,Pluckthun, A. (deposition date: 2011-07-16, release date: 2012-06-27, Last modification date: 2023-12-20) |
Primary citation | Kummer, L.,Parizek, P.,Rube, P.,Millgramm, B.,Prinz, A.,Mittl, P.R.,Kaufholz, M.,Zimmermann, B.,Herberg, F.W.,Pluckthun, A. Structural and Functional Analysis of Phosphorylation-Specific Binders of the Kinase Erk from Designed Ankyrin Repeat Protein Libraries. Proc.Natl.Acad.Sci.USA, 109:E2248-, 2012 Cited by PubMed: 22843676DOI: 10.1073/PNAS.1205399109 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.97 Å) |
Structure validation
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