3VJD

Crystal structure of the Y248A mutant of C(30) carotenoid dehydrosqualene synthase from Staphylococcus aureus

Summary for 3VJD

Entry DOI	10.2210/pdb3vjd/pdb
Related	2ZCO 2ZCP 2ZCQ 2ZCR 2ZCS 2ZY1 3VJE
Descriptor	Dehydrosqualene synthase, L(+)-TARTARIC ACID (3 entities in total)
Functional Keywords	crtm, carotenoid biosynthesis, staphyloxanthin biosynthesis, transferase, head-to-head condensation
Biological source	Staphylococcus aureus
Total number of polymer chains	1
Total formula weight	34845.49
Authors	Liu, C.I.,Jeng, W.Y.,Chang, W.J.,Wang, A.H.J. (deposition date: 2011-10-14, release date: 2012-04-11, Last modification date: 2023-11-08)
Primary citation	Liu, C.I.,Jeng, W.Y.,Chang, W.J.,Ko, T.P.,Wang, A.H.J. Binding modes of zaragozic acid A to human squalene synthase and staphylococcal dehydrosqualene synthase J.Biol.Chem., 287:18750-18757, 2012 Cited by PubMed: 22474324 DOI: 10.1074/jbc.M112.351254 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.48 Å)

Structure validation