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3SAI

Bacuills anthracis Dihydrofolate Reductase bound to propargyl-linked TMP analog, UCP1015

Summary for 3SAI
Entry DOI10.2210/pdb3sai/pdb
Related3E0B 3JVX 3JWM 3S9U 3SA1 3SA2
DescriptorDihydrofolate reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 6-ethyl-5-{3-[3-methoxy-5-(pyridin-4-yl)phenyl]prop-1-yn-1-yl}pyrimidine-2,4-diamine, ... (6 entities in total)
Functional Keywordsoxidoreductase
Biological sourceBacillus anthracis (anthrax,anthrax bacterium)
Total number of polymer chains2
Total formula weight41903.49
Authors
Anderson, A.C.,Beierlein, J.M. (deposition date: 2011-06-02, release date: 2012-06-13, Last modification date: 2023-09-13)
Primary citationAnderson, A.C.,Beierlein, J.M.,Viswanathan, K.,Wright, D.L.
SAR studies of heterocyclic propargyl-linked TMP analogs targeting Bacillus dihydrofolate reductase
To be Published,
Experimental method
X-RAY DIFFRACTION (2.25 Å)
Structure validation

221051

건을2024-06-12부터공개중

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