3RN8
Crystal Structure of iGluR2 Ligand Binding Domain and Symmetrical Carboxyl Containing Potentiator
Summary for 3RN8
Entry DOI | 10.2210/pdb3rn8/pdb |
Related | 1FTJ 1FTK 1FTL 1LB9 1LBC 3RNN |
Descriptor | Glutamate receptor 2, GLUTAMIC ACID, 3,3'-benzene-1,4-diylbis(4-cyano-5-ethylthiophene-2-carboxylic acid), ... (7 entities in total) |
Functional Keywords | glutamate receptor potentiator complex, ligand gated ion channel, membrane, transport protein |
Biological source | Homo sapiens (human) More |
Cellular location | Cell membrane ; Multi-pass membrane protein : P42262 |
Total number of polymer chains | 3 |
Total formula weight | 94596.11 |
Authors | Timm, D.E. (deposition date: 2011-04-22, release date: 2011-05-25, Last modification date: 2017-08-23) |
Primary citation | Timm, D.E.,Benveniste, M.,Weeks, A.M.,Nisenbaum, E.S.,Partin, K.M. Structural and functional analysis of two new positive allosteric modulators of GluA2 desensitization and deactivation. Mol.Pharmacol., 80:267-280, 2011 Cited by PubMed: 21543522DOI: 10.1124/mol.110.070243 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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