3RN8
Crystal Structure of iGluR2 Ligand Binding Domain and Symmetrical Carboxyl Containing Potentiator
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Glutamate receptor 2 | polymer | 280 | 30913.5 | 3 | UniProt (P42262) Pfam (PF10613) Pfam (PF00060) | Homo sapiens (human) | GluR-2, AMPA-selective glutamate receptor 2, GluR-B, GluR-K2, Glutamate receptor ionotropic, AMPA 2, GluA2 |
| 2 | D, F, M (A, B, C) | GLUTAMIC ACID | non-polymer | 147.1 | 3 | Chemie (GLU) | |||
| 3 | E, G (A, B) | 3,3'-benzene-1,4-diylbis(4-cyano-5-ethylthiophene-2-carboxylic acid) | non-polymer | 436.5 | 2 | Chemie (RN8) | |||
| 4 | H, I, J, N, O (B, C) | ZINC ION | non-polymer | 65.4 | 5 | Chemie (ZN) | |||
| 5 | K, P (B, C) | ACETATE ION | non-polymer | 59.0 | 2 | Chemie (ACT) | |||
| 6 | L (B) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 7 | Q, R, S (A, B, C) | water | water | 18.0 | 880 | Chemie (HOH) |
Sequence modifications
A, B, C: 3 - 117 (UniProt: P42262)
A, B, C: 120 - 279 (UniProt: P42262)
| PDB | External Database | Details |
|---|---|---|
| Arg 0 | - | expression tag |
| Gly 1 | - | expression tag |
| Ala 2 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 118 | - | linker |
| Thr 119 | - | linker |
| Gly 231 | Arg 764 | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 92740.5 | |
| Non-Polymers* | Number of molecules | 13 |
| Total formula weight | 1855.6 | |
| All* | Total formula weight | 94596.1 |
