3R4S
Cell entry of botulinum neurotoxin type C is dependent upon interaction with two ganglioside molecules
Summary for 3R4S
Entry DOI | 10.2210/pdb3r4s/pdb |
Related | 3R4U |
Descriptor | Botulinum neurotoxin type C1, N-acetyl-beta-neuraminic acid, N-acetyl-alpha-neuraminic acid, ... (4 entities in total) |
Functional Keywords | botulinum toxins, gangliosides, hydrolase |
Biological source | Clostridium botulinum |
Cellular location | Botulinum neurotoxin C1 light chain: Secreted. Botulinum neurotoxin C1 heavy chain: Secreted: P18640 |
Total number of polymer chains | 2 |
Total formula weight | 104057.78 |
Authors | Strotmeier, J.,Gu, S.,Jutzi, S.,Mahrhold, S.,Zhou, J.,Pich, A.,Bigalke, H.,Rummel, A.,Jin, R.,Binz, T. (deposition date: 2011-03-17, release date: 2011-06-08, Last modification date: 2024-02-21) |
Primary citation | Strotmeier, J.,Gu, S.,Jutzi, S.,Mahrhold, S.,Zhou, J.,Pich, A.,Eichner, T.,Bigalke, H.,Rummel, A.,Jin, R.,Binz, T. The biological activity of botulinum neurotoxin type C is dependent upon novel types of ganglioside binding sites. Mol.Microbiol., 81:143-156, 2011 Cited by PubMed: 21542861DOI: 10.1111/j.1365-2958.2011.07682.x PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.15 Å) |
Structure validation
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