3QNW
Caspase-6 in complex with Z-VAD-FMK inhibitor
Summary for 3QNW
Entry DOI | 10.2210/pdb3qnw/pdb |
Related | 3P45 3P4U |
Related PRD ID | PRD_000338 |
Descriptor | Caspase-6, Z-VAD-FMK, ... (4 entities in total) |
Functional Keywords | cysteine protease, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasm: P55212 P55212 |
Total number of polymer chains | 11 |
Total formula weight | 119011.01 |
Authors | Mueller, I.,Lamers, M.,Ritchie, A.,Park, H.,Dominguez, C.,Munoz, I.,Maillard, M.,Kiselyov, A. (deposition date: 2011-02-09, release date: 2011-09-21, Last modification date: 2023-09-13) |
Primary citation | Muller, I.,Lamers, M.B.,Ritchie, A.J.,Dominguez, C.,Munoz-Sanjuan, I.,Kiselyov, A. Structure of human caspase-6 in complex with Z-VAD-FMK: New peptide binding mode observed for the non-canonical caspase conformation. Bioorg.Med.Chem.Lett., 21:5244-5247, 2011 Cited by PubMed: 21820899DOI: 10.1016/j.bmcl.2011.07.041 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.65 Å) |
Structure validation
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