3P4U

Crystal structure of active caspase-6 in complex with Ac-VEID-CHO inhibitor

Summary for 3P4U

• Entry DOI: 10.2210/pdb3p4u/pdb
• Related: 3P45
• Related PRD ID: PRD_000929
• Descriptor: Caspase-6, Ac-VEID-CHO inhibitor, ... (4 entities in total)
• Functional Keywords: protease, caspase, huntington's disease, competitive inhibition, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Homo sapiens (human); More
• Cellular location: Cytoplasm: P55212 P55212
• Total number of polymer chains: 6
• Total formula weight: 63035.12

Authors

Mueller, I.,Lamers, M.B.A.C.,Ritchie, A.J.,Dominguez, C.,Munoz, I.,Maillard, M.,Kiselyov, A. (deposition date: 2010-10-07, release date: 2011-09-28, Last modification date: 2015-12-02)

• Primary citation: Mueller, I.,Lamers, M.B.A.C.,Ritchie, A.J.,Dominguez, C.,Munoz, I.,Maillard, M.,Kiselyov, A.; Crystal structures of active and inhibitor-bound human Casp6; To be Published,

Experimental method

X-RAY DIFFRACTION (1.9 Å)