3QH0
X-ray crystal structure of palmitic acid bound to the cyclooxygenase channel of cyclooxygenase-2
Summary for 3QH0
Entry DOI | 10.2210/pdb3qh0/pdb |
Related | 1CVU 1DIY 3HS5 3HS6 3HS7 5COX |
Descriptor | Prostaglandin G/H synthase 2, 2-acetamido-2-deoxy-beta-D-glucopyranose, octyl beta-D-glucopyranoside, ... (12 entities in total) |
Functional Keywords | biological dimer, oxidoreductase, n-glycosylation, monotopic membrane protein |
Biological source | Mus musculus (mouse) |
Total number of polymer chains | 2 |
Total formula weight | 145419.34 |
Authors | Vecchio, A.J.,Malkowski, M.G. (deposition date: 2011-01-25, release date: 2011-04-13, Last modification date: 2023-09-13) |
Primary citation | Dong, L.,Vecchio, A.J.,Sharma, N.P.,Jurban, B.J.,Malkowski, M.G.,Smith, W.L. Human cyclooxygenase-2 is a sequence homodimer that functions as a conformational heterodimer. J.Biol.Chem., 286:19035-19046, 2011 Cited by PubMed: 21467029DOI: 10.1074/jbc.M111.231969 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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