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3QH0

X-ray crystal structure of palmitic acid bound to the cyclooxygenase channel of cyclooxygenase-2

Summary for 3QH0
Entry DOI10.2210/pdb3qh0/pdb
Related1CVU 1DIY 3HS5 3HS6 3HS7 5COX
DescriptorProstaglandin G/H synthase 2, 2-acetamido-2-deoxy-beta-D-glucopyranose, octyl beta-D-glucopyranoside, ... (12 entities in total)
Functional Keywordsbiological dimer, oxidoreductase, n-glycosylation, monotopic membrane protein
Biological sourceMus musculus (mouse)
Total number of polymer chains2
Total formula weight145419.34
Authors
Vecchio, A.J.,Malkowski, M.G. (deposition date: 2011-01-25, release date: 2011-04-13, Last modification date: 2023-09-13)
Primary citationDong, L.,Vecchio, A.J.,Sharma, N.P.,Jurban, B.J.,Malkowski, M.G.,Smith, W.L.
Human cyclooxygenase-2 is a sequence homodimer that functions as a conformational heterodimer.
J.Biol.Chem., 286:19035-19046, 2011
Cited by
PubMed: 21467029
DOI: 10.1074/jbc.M111.231969
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.1 Å)
Structure validation

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