3QH0

X-ray crystal structure of palmitic acid bound to the cyclooxygenase channel of cyclooxygenase-2

3QH0 の概要

• エントリーDOI: 10.2210/pdb3qh0/pdb
• 関連するPDBエントリー: 1CVU 1DIY 3HS5 3HS6 3HS7 5COX
• 分子名称: Prostaglandin G/H synthase 2, 2-acetamido-2-deoxy-beta-D-glucopyranose, octyl beta-D-glucopyranoside, ... (12 entities in total)
• 機能のキーワード: biological dimer, oxidoreductase, n-glycosylation, monotopic membrane protein
• 由来する生物種: Mus musculus (mouse)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 145419.34

構造登録者

Vecchio, A.J.,Malkowski, M.G. (登録日: 2011-01-25, 公開日: 2011-04-13, 最終更新日: 2023-09-13)

• 主引用文献: Dong, L.,Vecchio, A.J.,Sharma, N.P.,Jurban, B.J.,Malkowski, M.G.,Smith, W.L.; Human cyclooxygenase-2 is a sequence homodimer that functions as a conformational heterodimer.; J.Biol.Chem., 286:19035-19046, 2011; PubMed: 21467029; DOI: 10.1074/jbc.M111.231969

実験手法

X-RAY DIFFRACTION (2.1 Å)