3PZB

Crystals Structure of Aspartate beta-Semialdehyde Dehydrogenase complex with NADP and D-2,3-Diaminopropionate

Summary for 3PZB

• Entry DOI: 10.2210/pdb3pzb/pdb
• Related: 2GZ1 3PWK 3PWS 3PYL 3PYX 3PZR 3Q0E 3Q11 3Q1L
• Descriptor: Aspartate-semialdehyde dehydrogenase, 3-amino-D-alanine, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... (6 entities in total)
• Functional Keywords: nadp, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor
• Biological source: Streptococcus pneumoniae
• Total number of polymer chains: 2
• Total formula weight: 82105.40

Authors

Pavlovsky, A.G.,Viola, R.E. (deposition date: 2010-12-14, release date: 2012-01-04, Last modification date: 2024-02-21)

• Primary citation: Pavlovsky, A.G.,Liu, X.,Faehnle, C.R.,Potente, N.,Viola, R.E.; Structural Characterization of Inhibitors with Selectivity against Members of a Homologous Enzyme Family.; Chem.Biol.Drug Des., 79:128-136, 2012; PubMed: 22039970; DOI: 10.1111/j.1747-0285.2011.01267.x

Experimental method

X-RAY DIFFRACTION (2 Å)