3PZB
Crystals Structure of Aspartate beta-Semialdehyde Dehydrogenase complex with NADP and D-2,3-Diaminopropionate
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004073 | molecular_function | aspartate-semialdehyde dehydrogenase activity |
| A | 0008652 | biological_process | amino acid biosynthetic process |
| A | 0009086 | biological_process | methionine biosynthetic process |
| A | 0009088 | biological_process | threonine biosynthetic process |
| A | 0009089 | biological_process | lysine biosynthetic process via diaminopimelate |
| A | 0009097 | biological_process | isoleucine biosynthetic process |
| A | 0016620 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor |
| A | 0046983 | molecular_function | protein dimerization activity |
| A | 0050661 | molecular_function | NADP binding |
| A | 0051287 | molecular_function | NAD binding |
| B | 0004073 | molecular_function | aspartate-semialdehyde dehydrogenase activity |
| B | 0008652 | biological_process | amino acid biosynthetic process |
| B | 0009086 | biological_process | methionine biosynthetic process |
| B | 0009088 | biological_process | threonine biosynthetic process |
| B | 0009089 | biological_process | lysine biosynthetic process via diaminopimelate |
| B | 0009097 | biological_process | isoleucine biosynthetic process |
| B | 0016620 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor |
| B | 0046983 | molecular_function | protein dimerization activity |
| B | 0050661 | molecular_function | NADP binding |
| B | 0051287 | molecular_function | NAD binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE 2RA B 367 |
| Chain | Residue |
| B | ASN127 |
| B | CYS128 |
| B | GLN155 |
| B | GLY159 |
| B | ILE209 |
| B | GLU220 |
| B | ARG245 |
| B | NAP368 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE 2RA A 367 |
| Chain | Residue |
| A | CYS128 |
| A | GLN155 |
| A | GLY159 |
| A | ILE209 |
| A | GLU220 |
| A | ARG245 |
| A | NAP368 |
| A | ASN127 |
| site_id | AC3 |
| Number of Residues | 29 |
| Details | BINDING SITE FOR RESIDUE NAP A 368 |
| Chain | Residue |
| A | GLY9 |
| A | THR11 |
| A | GLY12 |
| A | ALA13 |
| A | VAL14 |
| A | ALA36 |
| A | SER37 |
| A | ARG39 |
| A | SER40 |
| A | THR57 |
| A | SER71 |
| A | ALA72 |
| A | GLY73 |
| A | THR76 |
| A | ASN94 |
| A | THR95 |
| A | CYS128 |
| A | SER158 |
| A | GLY159 |
| A | GLY161 |
| A | MET162 |
| A | ASN325 |
| A | LEU326 |
| A | GLY329 |
| A | ALA330 |
| A | 2RA367 |
| A | HOH373 |
| A | HOH485 |
| A | HOH530 |
| site_id | AC4 |
| Number of Residues | 35 |
| Details | BINDING SITE FOR RESIDUE NAP B 368 |
| Chain | Residue |
| B | GLY9 |
| B | THR11 |
| B | GLY12 |
| B | ALA13 |
| B | VAL14 |
| B | ALA36 |
| B | SER37 |
| B | ARG39 |
| B | SER40 |
| B | THR57 |
| B | SER71 |
| B | ALA72 |
| B | GLY73 |
| B | THR76 |
| B | ASN94 |
| B | THR95 |
| B | CYS128 |
| B | SER158 |
| B | GLY159 |
| B | GLY161 |
| B | MET162 |
| B | ASN325 |
| B | LEU326 |
| B | GLY329 |
| B | ALA330 |
| B | 2RA367 |
| B | HOH377 |
| B | HOH424 |
| B | HOH458 |
| B | HOH531 |
| B | HOH537 |
| B | HOH579 |
| B | HOH598 |
| B | HOH614 |
| B | HOH618 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NA A 369 |
| Chain | Residue |
| A | ALA274 |
| A | PHE276 |
| A | ALA279 |
| A | HOH483 |
| B | GLU343 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO B 369 |
| Chain | Residue |
| A | THR26 |
| A | EDO370 |
| B | GLU24 |
| B | SER25 |
| B | TRP332 |
| B | GLU339 |
| B | HOH470 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO A 370 |
| Chain | Residue |
| A | GLU24 |
| A | SER25 |
| A | TRP332 |
| A | GLU339 |
| A | HOH377 |
| B | THR26 |
| B | EDO369 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 371 |
| Chain | Residue |
| A | SER250 |
| A | GLY298 |
| A | ASP324 |
| A | LEU326 |
| A | HOH533 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO B 370 |
| Chain | Residue |
| B | SER250 |
| B | GLY298 |
| B | ASP324 |
| B | LEU326 |
| B | HOH489 |
| site_id | BC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO B 371 |
| Chain | Residue |
| A | ASP312 |
| A | HOH503 |
| B | LYS229 |
