3Q1L

Crystals Structure of Aspartate beta-Semialdehyde Dehydrogenase from Streptococcus pneumoniae with cysteamine bound covalently to Cys 128

Summary for 3Q1L

• Entry DOI: 10.2210/pdb3q1l/pdb
• Related: 3PWK 3PWS 3PYL 3PYX 3PZB 3PZR 3Q0E 3Q11
• Descriptor: Aspartate beta-semialdehyde dehydrogenase, 2-AMINO-ETHANETHIOL (3 entities in total)
• Functional Keywords: nadp, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor
• Biological source: Streptococcus pneumoniae
• Total number of polymer chains: 4
• Total formula weight: 160462.69

Authors

Pavlovsky, A.G.,Viola, R.E. (deposition date: 2010-12-17, release date: 2012-01-04)

• Primary citation: Pavlovsky, A.G.,Liu, X.,Faehnle, C.R.,Potente, N.,Viola, R.E.; Structural Characterization of Inhibitors with Selectivity against Members of a Homologous Enzyme Family.; Chem.Biol.Drug Des., 79:128-136, 2012; PubMed: 22039970; DOI: 10.1111/j.1747-0285.2011.01267.x

Experimental method

X-RAY DIFFRACTION (2.3 Å)