3PWK
Crystal Structure of Aspartate beta-Semialdehide Dehydrogenase from Streptococcus pneumoniae with 2',5'-Adenosine diphosphate and D-2-aminoadipate
Summary for 3PWK
Entry DOI | 10.2210/pdb3pwk/pdb |
Related | 2GZ2 3PWS 3PYL 3PYX 3PZB 3PZR 3Q0E 3Q11 3Q1L |
Descriptor | Aspartate-semialdehyde dehydrogenase, 5'-O-MONOPHOSPHORYLADENYLYL(2'->5')ADENYLYL(2'->5')ADENOSINE, trans-cyclohexane-1,4-dicarboxylic acid, ... (6 entities in total) |
Functional Keywords | dehydrogenase, nadp binding, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor |
Biological source | Streptococcus pneumoniae |
Total number of polymer chains | 2 |
Total formula weight | 82975.19 |
Authors | Pavlovsky, A.G.,Viola, R.E. (deposition date: 2010-12-08, release date: 2012-01-04, Last modification date: 2023-09-13) |
Primary citation | Pavlovsky, A.G.,Liu, X.,Faehnle, C.R.,Potente, N.,Viola, R.E. Structural Characterization of Inhibitors with Selectivity against Members of a Homologous Enzyme Family. Chem.Biol.Drug Des., 79:128-136, 2012 Cited by PubMed: 22039970DOI: 10.1111/j.1747-0285.2011.01267.x PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.5 Å) |
Structure validation
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