3PY1

CDK2 ternary complex with SU9516 and ANS

Summary for 3PY1

Related3PXF 3PXQ 3PXR 3PXY 3PXZ 3PY0
DescriptorCell division protein kinase 2, 1,2-ETHANEDIOL, (3Z)-3-(1H-IMIDAZOL-5-YLMETHYLENE)-5-METHOXY-1H-INDOL-2(3H)-ONE, ... (5 entities in total)
Functional Keywordsprotein kinase, cdk2, allosteric ligand, ans, transferase-transferase inhibitor complex, transferase/transferase inhibitor
Biological sourceHomo sapiens (human)
Total number of polymer chains1
Total molecular weight35663.35
Authors
Betzi, S.,Alam, R.,Schonbrunn, E. (deposition date: 2010-12-10, release date: 2011-02-16, Last modification date: 2011-07-13)
Primary citation
Betzi, S.,Alam, R.,Martin, M.,Lubbers, D.J.,Han, H.,Jakkaraj, S.R.,Georg, G.I.,Schonbrunn, E.
Discovery of a Potential Allosteric Ligand Binding Site in CDK2.
Acs Chem.Biol., 6:492-501, 2011
PubMed: 21291269 (PDB entries with the same primary citation)
DOI: 10.1021/cb100410m
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.05 Å)
?

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.251121.0%0.7%10.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution