CDK2 ternary complex with JWS648 and ANS

Summary for 3PXZ

Related3PXF 3PXQ 3PXR 3PXY 3PY0 3PY1
DescriptorCell division protein kinase 2, 8-ANILINO-1-NAPHTHALENE SULFONATE, 2-(4,6-diamino-1,3,5-triazin-2-yl)-4-methoxyphenol, ... (4 entities in total)
Functional Keywordsprotein kinase, cdk2, allosteric ligand, ans, transferase-transferase inhibitor complex, transferase/transferase inhibitor
Biological sourceHomo sapiens (human)
Total number of polymer chains1
Total molecular weight35593.26
Betzi, S.,Alam, R.,Schonbrunn, E. (deposition date: 2010-12-10, release date: 2011-02-16, Last modification date: 2011-07-13)
Primary citation
Betzi, S.,Alam, R.,Martin, M.,Lubbers, D.J.,Han, H.,Jakkaraj, S.R.,Georg, G.I.,Schonbrunn, E.
Discovery of a Potential Allosteric Ligand Binding Site in CDK2.
Acs Chem.Biol., 6:492-501, 2011
PubMed: 21291269 (PDB entries with the same primary citation)
DOI: 10.1021/cb100410m
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.24815 1.0% 1.9% 15.6%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
PDB entries from 2020-10-28