3PXY
CDK2 in complex with inhibitor JWS648
Summary for 3PXY
| Entry DOI | 10.2210/pdb3pxy/pdb |
| Related | 3PXF 3PXQ 3PXR 3PXZ 3PY0 3PY1 |
| Descriptor | Cell division protein kinase 2, 2-(4,6-diamino-1,3,5-triazin-2-yl)-4-methoxyphenol, PHOSPHATE ION, ... (4 entities in total) |
| Functional Keywords | protein kinase, cdk2, inhibitor, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 1 |
| Total formula weight | 35089.55 |
| Authors | Han, H.,Betzi, S.,Alam, R.,Schonbrunn, E. (deposition date: 2010-12-10, release date: 2011-02-16, Last modification date: 2023-09-13) |
| Primary citation | Betzi, S.,Alam, R.,Martin, M.,Lubbers, D.J.,Han, H.,Jakkaraj, S.R.,Georg, G.I.,Schonbrunn, E. Discovery of a Potential Allosteric Ligand Binding Site in CDK2. Acs Chem.Biol., 6:492-501, 2011 Cited by PubMed: 21291269DOI: 10.1021/cb100410m PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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