3OY4
Crystal Structure of HIV-1 L76V Protease in Complex with the Protease Inhibitor Darunavir.
Summary for 3OY4
Entry DOI | 10.2210/pdb3oy4/pdb |
Related | 3OXV 3OXW 3OXX |
Descriptor | HIV-1 PROTEASE, PHOSPHATE ION, ACETATE ION, ... (5 entities in total) |
Functional Keywords | hiv-1 protease, inhibitor resistance, aids, aspartyl protease, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Human immunodeficiency virus type 1 (HIV-1) |
Cellular location | Gag-Pol polyprotein: Host cell membrane; Lipid-anchor. Matrix protein p17: Virion membrane; Lipid- anchor . Capsid protein p24: Virion . Nucleocapsid protein p7: Virion . Reverse transcriptase/ribonuclease H: Virion . Integrase: Virion : P03369 |
Total number of polymer chains | 2 |
Total formula weight | 22944.38 |
Authors | Schiffer, C.A.,Nalivaika, E.A.,Bandaranayake, R.M. (deposition date: 2010-09-22, release date: 2011-02-09, Last modification date: 2024-02-21) |
Primary citation | Schiffer, C.A.,Nalivaika, E.A.,Bandaranayake, R.M. Crystal Structure of HIV-1 L76V Protease in Complex with the Protease Inhibitor Darunavir. To be Published, |
Experimental method | X-RAY DIFFRACTION (1.76 Å) |
Structure validation
Download full validation report