3OY4

Crystal Structure of HIV-1 L76V Protease in Complex with the Protease Inhibitor Darunavir.

3OY4 の概要

• エントリーDOI: 10.2210/pdb3oy4/pdb
• 関連するPDBエントリー: 3OXV 3OXW 3OXX
• 分子名称: HIV-1 PROTEASE, PHOSPHATE ION, ACETATE ION, ... (5 entities in total)
• 機能のキーワード: hiv-1 protease, inhibitor resistance, aids, aspartyl protease, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• 由来する生物種: Human immunodeficiency virus type 1 (HIV-1)
• 細胞内の位置: Gag-Pol polyprotein: Host cell membrane; Lipid-anchor. Matrix protein p17: Virion membrane; Lipid- anchor . Capsid protein p24: Virion . Nucleocapsid protein p7: Virion . Reverse transcriptase/ribonuclease H: Virion . Integrase: Virion : P03369
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 22944.38

構造登録者

Schiffer, C.A.,Nalivaika, E.A.,Bandaranayake, R.M. (登録日: 2010-09-22, 公開日: 2011-02-09, 最終更新日: 2024-02-21)

• 主引用文献: Schiffer, C.A.,Nalivaika, E.A.,Bandaranayake, R.M.; Crystal Structure of HIV-1 L76V Protease in Complex with the Protease Inhibitor Darunavir.; To be Published,

実験手法

X-RAY DIFFRACTION (1.76 Å)