3O0G

Crystal Structure of Cdk5:p25 in complex with an ATP analogue

Summary for 3O0G

• Entry DOI: 10.2210/pdb3o0g/pdb
• Related: 3O0S
• Descriptor: Cell division protein kinase 5, Cyclin-dependent kinase 5 activator 1, {4-amino-2-[(4-chlorophenyl)amino]-1,3-thiazol-5-yl}(3-nitrophenyl)methanone, ... (4 entities in total)
• Functional Keywords: kinase, kinase activator complex, kinase inhibitor complex, transferase-transferase activator complex, transferase/transferase activator
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 4
• Total formula weight: 101507.46

Authors

Mapelli, M. (deposition date: 2010-07-19, release date: 2011-01-26, Last modification date: 2023-09-06)

• Primary citation: Ahn, J.S.,Radhakrishnan, M.L.,Mapelli, M.,Choi, S.,Tidor, B.,Cuny, G.D.,Musacchio, A.,Yeh, L.,Kosik, S.K.; Defining Cdk5 ligand chemical space with small molecule inhibitors of Tau phosphorylation; Chem.Biol., 12:811-823, 2005; PubMed: 16039528; DOI: 10.1016/j.chembiol.2005.05.011

Experimental method

X-RAY DIFFRACTION (1.95 Å)