3LO5
Crystal Structure of the dominant negative S17N mutant of Ras
Summary for 3LO5
Entry DOI | 10.2210/pdb3lo5/pdb |
Related | 4Q21 |
Descriptor | GTPase HRas, GUANOSINE-5'-DIPHOSPHATE, CALCIUM ION, ... (5 entities in total) |
Functional Keywords | ras, nucleotide exchange, dominant negative, mg2+, acetylation, cell membrane, disease mutation, golgi apparatus, gtp-binding, lipoprotein, membrane, methylation, nucleotide-binding, palmitate, prenylation, proto-oncogene, s-nitrosylation, oncoprotein |
Biological source | Homo sapiens (human) |
Cellular location | Cell membrane; Lipid-anchor; Cytoplasmic side: P01112 |
Total number of polymer chains | 3 |
Total formula weight | 58292.63 |
Authors | Nassar, N.,Singh, K.,Garcia-Diaz, M. (deposition date: 2010-02-03, release date: 2010-03-02, Last modification date: 2023-09-06) |
Primary citation | Nassar, N.,Singh, K.,Garcia-Diaz, M. Structure of the Dominant Negative S17N Mutant of Ras Biochemistry, 49:1970-1974, 2010 Cited by PubMed: 20131908DOI: 10.1021/bi9020742 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.568 Å) |
Structure validation
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