3LO5
Crystal Structure of the dominant negative S17N mutant of Ras
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E | GTPase HRas | polymer | 166 | 18902.2 | 3 | UniProt (P01112) Pfam (PF00071) In PDB | Homo sapiens (human) | Transforming protein p21, p21ras, H-Ras-1, c-H-ras, Ha-Ras, GTPase HRas, N-terminally processed |
| 2 | A, C, E | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 3 | Chemie (GDP) | |||
| 3 | A, C, E | CALCIUM ION | non-polymer | 40.1 | 4 | Chemie (CA) | |||
| 4 | C | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 5 | water | water | 18.0 | 66 | Chemie (HOH) |
Sequence modifications
A, C, E: 1 - 166 (UniProt: P01112)
| PDB | External Database | Details |
|---|---|---|
| Asn 17 | Ser 17 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 56706.7 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1586.0 | |
| All* | Total formula weight | 58292.6 |
