3LIT
The crystal structure of htlv protease complexed with the inhibitor KNI-10681
Summary for 3LIT
Entry DOI | 10.2210/pdb3lit/pdb |
Related | 2B7F 3LIN 3LIQ 3LIV 3LIX 3LIY |
Related PRD ID | PRD_000579 |
Descriptor | Protease, (4R)-3-[(2S,3S)-3-[[(2S)-2-[[(2S)-2-azanyl-2-phenyl-ethanoyl]amino]-3,3-dimethyl-butanoyl]amino]-2-hydroxy-4-phenyl-but anoyl]-5,5-dimethyl-N-[(2R)-3-methylbutan-2-yl]-1,3-thiazolidine-4-carboxamide (3 entities in total) |
Functional Keywords | hydrolase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Human T-lymphotropic virus 1 |
Total number of polymer chains | 2 |
Total formula weight | 25787.03 |
Authors | Satoh, T.,Li, M.,Nguyen, J.,Kiso, Y.,Wlodawer, A.,Gustchina, A. (deposition date: 2010-01-25, release date: 2010-07-14, Last modification date: 2023-09-06) |
Primary citation | Satoh, T.,Li, M.,Nguyen, J.T.,Kiso, Y.,Gustchina, A.,Wlodawer, A. Crystal structures of inhibitor complexes of human T-cell leukemia virus (HTLV-1) protease. J.Mol.Biol., 401:626-641, 2010 Cited by PubMed: 20600105DOI: 10.1016/j.jmb.2010.06.052 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.19 Å) |
Structure validation
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