3LIT
The crystal structure of htlv protease complexed with the inhibitor KNI-10681
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Protease | polymer | 116 | 12566.6 | 2 | UniProt (Q82134) Pfam (PF00077) In PDB | Human T-lymphotropic virus 1 | |
| 2 | A | (4R)-3-[(2S,3S)-3-[[(2S)-2-[[(2S)-2-azanyl-2-phenyl-ethanoyl]amino]-3,3-dimethyl-butanoyl]amino]-2-hydroxy-4-phenyl-but anoyl]-5,5-dimethyl-N-[(2R)-3-methylbutan-2-yl]-1,3-thiazolidine-4-carboxamide | non-polymer | 653.9 | 1 | BIRD (PRD_000579) Chemie (E15) | |||
| 3 | water | water | 18.0 | 66 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 116 (UniProt: Q82134)
| PDB | External Database | Details |
|---|---|---|
| Ile 40 | Leu 40 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 25133.2 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 653.9 | |
| All* | Total formula weight | 25787.0 |
