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3LIT

The crystal structure of htlv protease complexed with the inhibitor KNI-10681

Functional Information from GO Data
ChainGOidnamespacecontents
A0004190molecular_functionaspartic-type endopeptidase activity
A0006508biological_processproteolysis
A0008233molecular_functionpeptidase activity
A0046872molecular_functionmetal ion binding
B0004190molecular_functionaspartic-type endopeptidase activity
B0006508biological_processproteolysis
B0008233molecular_functionpeptidase activity
B0046872molecular_functionmetal ion binding
Functional Information from PDB Data
site_idAC1
Number of Residues20
DetailsBINDING SITE FOR RESIDUE E15 A 117
ChainResidue
AARG10
AHOH118
AHOH127
AHOH139
BLEU30
BASP32
BGLY34
BASP36
BMET37
BVAL56
BLEU57
AASP32
BALA59
AGLY34
AALA35
AMET37
AVAL56
ALEU57
AALA59
ATRP98

Functional Information from PROSITE/UniProt
site_idPS00141
Number of Residues12
DetailsASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. ALLDTGADMTVI
ChainResidueDetails
AALA29-ILE40

219140

PDB entries from 2024-05-01

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