3L8B

Crystal structure of a replicative DNA polymerase bound to the oxidized guanine lesion guanidinohydantoin

3L8B の概要

• エントリーDOI: 10.2210/pdb3l8b/pdb
• 関連するPDBエントリー: 1IG9 1Q9Y 2DY4 2P5O
• 分子名称: DNA polymerase, DNA (5'-D(*AP*C*TP*(G35)P*TP*TP*AP*AP*GP*CP*AP*GP*TP*CP*CP*GP*CP*G)-3'), DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*A)-3'), ... (5 entities in total)
• 機能のキーワード: dna polymerase rb69 gp43, protein-dna complex, oxidative dna lesion, guanidinohydantoin, dna replication, dna-binding, dna-directed dna polymerase, exonuclease, hydrolase, nuclease, nucleotidyltransferase, transferase, transferase-dna complex, transferase/dna
• 由来する生物種: Enterobacteria phage RB69 (Bacteriophage RB69)
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 229359.68

構造登録者

Aller, P.,Ye, Y.,Wallace, S.S.,Burrows, C.J.,Doublie, S. (登録日: 2009-12-30, 公開日: 2010-03-09, 最終更新日: 2023-09-06)

• 主引用文献: Aller, P.,Ye, Y.,Wallace, S.S.,Burrows, C.J.,Doublie, S.; Crystal structure of a replicative DNA polymerase bound to the oxidized guanine lesion guanidinohydantoin.; Biochemistry, 49:2502-2509, 2010; PubMed: 20166752; DOI: 10.1021/bi902195p

実験手法

X-RAY DIFFRACTION (2.15 Å)