3KHJ
C. parvum inosine monophosphate dehydrogenase bound by inhibitor C64
Summary for 3KHJ
Entry DOI | 10.2210/pdb3khj/pdb |
Related | 1LRT 1NF7 1NFB 1PVN 1ZFJ |
Descriptor | Inosine-5-monophosphate dehydrogenase, INOSINIC ACID, N-(4-bromophenyl)-2-[2-(1,3-thiazol-2-yl)-1H-benzimidazol-1-yl]acetamide, ... (5 entities in total) |
Functional Keywords | enzyme-inhibitor complex, oxidoreductase |
Biological source | Cryptosporidium parvum More |
Total number of polymer chains | 8 |
Total formula weight | 312216.09 |
Authors | MacPherson, I.S.,Hedstrom, L.K. (deposition date: 2009-10-30, release date: 2010-02-02, Last modification date: 2024-02-21) |
Primary citation | Macpherson, I.S.,Kirubakaran, S.,Gorla, S.K.,Riera, T.V.,D'Aquino, J.A.,Zhang, M.,Cuny, G.D.,Hedstrom, L. The structural basis of Cryptosporidium -specific IMP dehydrogenase inhibitor selectivity. J.Am.Chem.Soc., 132:1230-1231, 2010 Cited by PubMed: 20052976DOI: 10.1021/ja909947a PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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