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4E43

HIV protease (PR) dimer with acetate in exo site and peptide in active site

Replaces:  3KF1
Summary for 4E43
Entry DOI10.2210/pdb4e43/pdb
Related3KF1
DescriptorProtease, Random peptide, DIMETHYL SULFOXIDE, ... (7 entities in total)
Functional Keywordshiv-1 protease, exo site, aspartyl protease, fragment screen, hydrolase
Biological sourceHuman immunodeficiency virus 1
More
Total number of polymer chains3
Total formula weight23779.24
Authors
Stout, C.D. (deposition date: 2012-03-11, release date: 2012-05-30, Last modification date: 2024-02-28)
Primary citationPerryman, A.L.,Zhang, Q.,Soutter, H.H.,Rosenfeld, R.,McRee, D.E.,Olson, A.J.,Elder, J.E.,Stout, C.D.
Fragment-based screen against HIV protease.
Chem.Biol.Drug Des., 75:257-268, 2010
Cited by
PubMed: 20659109
DOI: 10.1111/j.1747-0285.2009.00943.x
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.54 Å)
Structure validation

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