Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| B | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE DMS A 101 |
| Chain | Residue |
| A | ARG87 |
| A | ASN88 |
| A | THR91 |
| B | LEU5 |
| B | TRP6 |
| B | ARG41 |
| B | HOH208 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE DMS A 102 |
| Chain | Residue |
| A | ASN88 |
| B | ARG41 |
| A | GLY73 |
| A | THR74 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ACT A 103 |
| Chain | Residue |
| A | LYS14 |
| A | GLY16 |
| A | GLY17 |
| A | LEU63 |
| A | GLU65 |
| A | GOL104 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL A 104 |
| Chain | Residue |
| A | GLY16 |
| A | PRO39 |
| A | ILE62 |
| A | LEU63 |
| A | ACT103 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL A 105 |
| Chain | Residue |
| A | GLN92 |
| A | ILE93 |
| A | GLY94 |
| B | DMS101 |
| B | HOH253 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL A 106 |
| Chain | Residue |
| A | PRO1 |
| A | GLN2 |
| B | GLU35 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL A 107 |
| Chain | Residue |
| A | LYS43 |
| A | GLN58 |
| A | ASP60 |
| B | HOH280 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE DMS B 101 |
| Chain | Residue |
| A | GOL105 |
| B | LYS55 |
| B | ARG57 |
| B | VAL77 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE DMS B 102 |
| Chain | Residue |
| A | GLY94 |
| B | GLN2 |
| B | LYS55 |
| site_id | BC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE BME B 103 |
| Chain | Residue |
| A | GLN18 |
| A | MET36 |
| A | ASN37 |
| B | GLU65 |
| B | GLY68 |
| site_id | BC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL B 104 |
| Chain | Residue |
| A | TRP6 |
| B | ARG87 |
| B | ASN88 |
| B | THR91 |
| B | HOH202 |
| B | HOH220 |
| site_id | BC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL B 105 |
| Chain | Residue |
| B | ASP30 |
| B | THR74 |
| B | ASN88 |
| B | HOH207 |
| B | HOH224 |
| B | HOH277 |
| site_id | BC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL B 106 |
| Chain | Residue |
| B | ARG41 |
| B | GLN58 |
| B | ASP60 |
| B | HOH270 |
| site_id | BC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL B 107 |
| Chain | Residue |
| A | THR4 |
| A | LEU5 |
| A | TRP6 |
| B | THR91 |
| B | CYS95 |
| B | HOH281 |
| site_id | BC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL B 108 |
| Chain | Residue |
| B | ILE15 |
| B | GLY16 |
| B | ILE62 |
| B | LEU63 |
| B | GOL109 |
| B | HOH258 |
| site_id | BC7 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE GOL B 109 |
| Chain | Residue |
| B | LYS14 |
| B | GLY16 |
| B | GLY17 |
| B | LEU63 |
| B | ILE64 |
| B | GLU65 |
| B | LYS70 |
| B | GOL108 |
| B | HOH287 |
Functional Information from PROSITE/UniProt
| site_id | PS00141 |
| Number of Residues | 12 |
| Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. ALLDTGADDTVL |
| Chain | Residue | Details |
| A | ALA22-LEU33 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI2 |
| Number of Residues | 20 |
| Details | Region: {"description":"Dimerization of protease","evidences":[{"source":"UniProtKB","id":"P04585","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Active site: {"description":"For protease activity; shared with dimeric partner","evidences":[{"source":"PROSITE-ProRule","id":"PRU10094","evidenceCode":"ECO:0000255"}]} |
