3K8Y
Allosteric modulation of H-Ras GTPase
Summary for 3K8Y
| Entry DOI | 10.2210/pdb3k8y/pdb |
| Related | 2RGE 3K9L 3K9N |
| Descriptor | GTPase HRas, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, CALCIUM ION, ... (6 entities in total) |
| Functional Keywords | protein-nucleotide complex, acetylation, cell membrane, disease mutation, golgi apparatus, gtp-binding, lipoprotein, membrane, methylation, nucleotide-binding, palmitate, prenylation, proto-oncogene, s-nitrosylation, oncoprotein |
| Biological source | Homo sapiens (human) |
| Cellular location | Cell membrane. Isoform 2: Nucleus: P01112 |
| Total number of polymer chains | 1 |
| Total formula weight | 19585.20 |
| Authors | Holzapfel, G.,Buhrman, G.,Mattos, C. (deposition date: 2009-10-15, release date: 2010-03-02, Last modification date: 2023-09-06) |
| Primary citation | Buhrman, G.,Holzapfel, G.,Fetics, S.,Mattos, C. Allosteric modulation of Ras positions Q61 for a direct role in catalysis. Proc.Natl.Acad.Sci.USA, 107:4931-4936, 2010 Cited by PubMed: 20194776DOI: 10.1073/pnas.0912226107 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.3 Å) |
Structure validation
Download full validation report
